From: Daniel on
Hi, i have some problems with estimating my signal-to-noise ratio for a combined signal + background.

1. I have a well defined signal
2. I have a well defined background
3. Calculations of SNR, when the signal and background are not putted together via SNR=(signal_max-background_mean)/background_std gives a SNR=4.

4. Now, i have put the signal in the noisy image and want to estimate the SNR, how should i do? i have tried to select a specific ROI (region of interest) and use the formula above? but my SNR are reduced with 50%

any suggestions?

/Daniel