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From: Stephen on 30 Apr 2010 14:14
First, I have to confess that I am new to Simbiology.

I followed the SimBiology Online Tutorial, BTW, it is a great tutorial. In the demo, when the sensitivity analysis was performed on the apoptosis model, the author got the most sensitivity to XIAP. All other species also have some sensitivity but to less degrees.

I exported the apoptosis model as SBML and then imported the SBML into my project as another model session. When the sensitivity analysis was performed, I got complete different results - only Casp3* and XIAP had good sensitivities and all other species got NO sensitivity at all. I compared both models - the author's original one and the re-imported SBML model, they seem to have identical info - species concentration, parameters, etc. I am really puzzled why after export/import of the same model, the sensitivity analysis became completely different.

Any help is greatly appreciated!
From: Arthur Goldsipe on 3 May 2010 15:11
"Stephen " <stephenswang(a)yahoo.com> wrote in message <hrf6lc$5of$1(a)fred.mathworks.com>...
> First, I have to confess that I am new to Simbiology.
>
> I followed the SimBiology Online Tutorial, BTW, it is a great tutorial. In the demo, when the sensitivity analysis was performed on the apoptosis model, the author got the most sensitivity to XIAP. All other species also have some sensitivity but to less degrees.
>
> I exported the apoptosis model as SBML and then imported the SBML into my project as another model session. When the sensitivity analysis was performed, I got complete different results - only Casp3* and XIAP had good sensitivities and all other species got NO sensitivity at all. I compared both models - the author's original one and the re-imported SBML model, they seem to have identical info - species concentration, parameters, etc. I am really puzzled why after export/import of the same model, the sensitivity analysis became completely different.

Hi Stephen,

When you export the model to SBML, it doesn't export the information stored under Configuration Settings. So when you loaded the SBML file, you get the default StopTime of 10. If you manually change the StopTime to 100000, you should be able to reproduce the results from the webinar tutorial.

Please post again if you have any other questions.

--Arthur
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