Never realized the Brits had such a terrible secret weapon (Rowland)
in [UK Mac]
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From: Mark Conrad on 19 Jul 2010 10:15 Rowland, using another of your great literary techniques, long rambling posts, here is another example, this time from a prestigious medical site: www.infectiousdiseasenews.com/article/65702.aspx Gastrointestinal Infections Posted June 21, 2010 Fecal bacteriotherapy may be effective in treating relapsing C. difficile infection A 2-year-old girl received a successful fecal transplant that resolved an ongoing battle with a Clostridium difficile infection that several antibiotic regimens failed to cure, according to a recently published case study. Researchers from Massachusetts General Hospital and Harvard Medical School noted that the patient presented to her primary care provider with a 1-week history of abdominal discomfort and loose stools containing blood and mucus. After C. difficile toxin was identified in her stool, she was administered a 10-day course of metronidazole (125 g orally three times daily) that resolved abdominal pains but not the diarrhea. The abdominal cramps recrudesced, at which point physicians administered a 30-day course of vancomycin at 125 mg orally four times daily and long-term probiotic therapy with Lactobacillus rhamnosus GG. Two days after the discontinuation of vancomycin, symptoms and bloody diarrhea returned, along with laboratory results that confirmed that C. difficile toxin. Vancomycin treatment was reinitiated and augmented with rifamixin 100 mg orally three times daily. A probiotic regimen of Saccharomyces boulardii and L. rhamnosus GG accompanied the antibiotics. This regimen was effective until 14 days after rifamixin was discontinued, when bloody diarrhea recurred despite ongoing vancomycin treatment. As vancomycin therapy continued, metronidazole 100 mg four times daily for an additional 14 days replaced the rifamixin treatment. Symptoms and abnormal stools resolved during treatment with metronidazole and over an eight-week period in which vancomycin therapy was tapered. Another relapse occurred four days after vancomycin was discontinued. Analysis of C. difficile toxin taken from the patient�s stool at this time indicated that in comparison with minimum inhibitory concentrations (MICs) for more than 200 toxin-producing strains, the vancomycin and metronidazole MICs for this strain were at or below the MIC90, according to the results. At this stage, staggered antibiotic treatment was initiated. The schedule was as follows: vancomycin for 2 weeks; nitazoxanide 100 mg orally twice daily for 3 days; vancomycin for 2 weeks; rifamixin 125 mg orally twice daily for 7 days; and then a course of pulsed-dose vancomycin every third day tapered over a 6-week period. This regimen was administered concomitantly with the aforementioned probiotics. The patient�s condition normalized during this treatment, but loose stools with mucus and abdominal pain returned when antibiotic therapy ceased. The clinicians conducted a fecal transplant using the patient�s father � who had a negative screening test result � as a donor. Bacteriotherapy protocol was modified to suit the young patient. Abdominal symptoms and diarrhea resolved within 36 hours of transplantation. Follow-up tests at 2 weeks, 3 months and 6 months yielded negative C. difficile toxin results and no symptoms or abnormal stools. A possible explanation for the efficacy of fecal transplantation is that the �donors� robust and diverse gut microbiota or other soluble compounds in the stool suppress C. difficile by competition for intestinal barrier function or tissue repair,� the researchers wrote. Other possible ways fecal bacteria may modulate the immunity of the recipient include secreting antimicrobial substances, upregulating anti-inflammatory factors, suppressing pro-inflammatory factors, triggering protective innate immune responses or stimulating phagocytes, natural killer cells and regulatory T cells, according to the researchers. �We have demonstrated that fecal bacteriotherapy may well prove to be a practical and effective therapy for relapsing [C. difficile infection] in young children,� they wrote. However, �until the effectiveness and safety of the proposed protocol can be evaluated further, this strategy should be reserved for children in whom appropriate antibiotics have failed in the setting of severe or prolonged symptomatic disease.� Russell G. Pediatrics. 2010;doi:10.1542/peds.2009.3363.
From: Mark Conrad on 19 Jul 2010 10:32 In article <timstreater-129B48.13275219072010(a)news.individual.net>, Tim Streater <timstreater(a)waitrose.com> wrote: > > Really Rowland ? 300 million Americans do not think so, > > and they are free to live anywhere else they want to > > Well no, they're not. They'll needs visas, work permits, residence > permits, same as anyone else moving to whatever the country happens to > be. They may be free to *leave* the US, like most people in civilised > countries are, but that's not the point. So _that_ is the secret, let me write that down, and here we dumb colonists have been letting millions of Mexicans and other South American illegal immigrants swarm into our USA , letting Obama our president put them all on our already burdened health care system - - - offering them amnesty periodically, even passing laws to force our English speaking citizens to print everything in two languages, because the illegals refuse to learn our native English here in the USA . Geeze, we never even thought of your simple solution, namely make things so tough on the illegals that they would leave the USA. One of our states, Arizona, passed a law to enforce our present laws about illegal immigration, but our erstwhile president Obama is busy trying to force mean old Arizona from enforcing existing law. Obama will likely succeed, because he has the political clout. Mark-
From: Rowland McDonnell on 19 Jul 2010 15:36 Peter Ceresole <peter(a)cara.demon.co.uk> wrote: > Mark Conrad <aeiou(a)mostly.invalid> wrote: > > > So you _do_ acknowledge that you started it first! Now, don't you > > feel better now that you admitted that ? > > For god's sake, you two, can it. > > Rowland *can't* stop; he's (really) mad. But surely you have enough self > control, so why don't you just stop it? > > Although this is Usenet, so maybe not. <cough> Peter, please stop jumping into threads with your grossly insulting opinions about me. It's really not at all polite beheviour, you know. And since this newsgroup was created for technical discussions about Macs, it's really very unwelcome, you doing this sort of thing. No-one here appreciates your `interventions' - you need to recognise that your behaviour here is not appropriate. Peter suffers from this compulsion to stick his oar to make pejorative remarks about me - he likes causing trouble here, whipping up bad feeling about me and all that. He *CAN'T* stop this antisocial behaviour - something to do with the effects of aging, I gather, but it's best to try to ignore him when he's in this mode. Rowland. P.S. Peter's opinions on me are ignorant and insulting in this case. He really has no idea what the hell he's talking about. He's developed a fantasy about me and he tries to get everyone else to believe it - he's obviously suffering from some sort of uncontrollable morbid compulsion. He's quite old - that might have something to do with it. -- Remove the animal for email address: rowland.mcdonnell(a)dog.physics.org Sorry - the spam got to me http://www.mag-uk.org http://www.bmf.co.uk UK biker? Join MAG and the BMF and stop the Eurocrats banning biking
From: Jim on 19 Jul 2010 15:46 Rowland McDonnell <real-address-in-sig(a)flur.bltigibbet.invalid> wrote: > And since this newsgroup was created for technical discussions about > Macs, Then why don't you stick to that and just ignore people who are, surely, not worth your time? Jim -- "Microsoft admitted its Vista operating system was a 'less good product' in what IT experts have described as the most ambitious understatement since the captain of the Titanic reported some slightly damp tablecloths." http://www.thedailymash.co.uk/
From: Rowland McDonnell on 19 Jul 2010 16:01
Mark Conrad <aeiou(a)mostly.invalid> wrote: > Rowland McDonnell <real-address-in-sig(a)flur.bltigibbet.invalid> wrote: > > > > Those insults of yours to me eleven days ago are the reason > > > that I insulted you in return, Rowland. > > > > Excuse me? > > > > `He started it Miss' is your justification? Well, the teachers I had an > > Infants' School would not accept that reason. Nor would any judge in > > court. > > So you _do_ acknowledge that you started it first! Now, don't you > feel better now that you admitted that ? You have just failed your school entry English comprehension exam. You have also failed your `honesty' exam - you see, I explained very carefully in my post that I started posting rude things about you only after *YOU* had turned up in this newsgroup for the technical discussion of Macs for UK people and - well, what did you do? You snipped what I explained about your filthy misbehaviour, didn't you? You lied, you pretended that you'd not read what I'd written, tried to pretend that it did not exist. What you did with your outrageous behaviour was remove all my points, including this fact: "You turned up here and you insulted my country, insulted my people, insulted *ME* quite viciously, insulted the very underpinnings of my culture, insulted the heart of what I live by - and you expect me to sit back and say *nothing*?" You have now shown your true colours. You are ignorant, you are rude, you are dishonest. You are trying to use vicious lying Republican bullying on a decent honest Englishman. You are promoting race hatred and intolerance of dissent, and other great social ills. And like all other decent honest Englishman[1], I don't like it, don't like it one little bit. N.B: despite appearances, I'm a lot more like Jeeves than Bertie W. Now all I'm going to say is: Get out! Your sort is not welcome here. [snip piles and piles of filthy dishonest abuse] Rowland. [1] I said `decent honest' Englishman. Leave the other sort of Englishman to us, thank you. We understand them, and we know how to deal with them. P.S. This newsgroup is for UK types to talk about Macs. It's not here for neo-Nazi American bigots like yourself (aka Republicans) to push your Party's disgusting lies. Get out! You are not welcome! -- Remove the animal for email address: rowland.mcdonnell(a)dog.physics.org Sorry - the spam got to me http://www.mag-uk.org http://www.bmf.co.uk UK biker? Join MAG and the BMF and stop the Eurocrats banning biking |